In the biotechnology industry, to develop new medications for various diseases, they must do pre-clinical research and experiment before the market existence. The entire drug development process involves several months to years for testing and investigation. This article explains the pre-clinical research in the pharmaceutical industry and its testing types.
Overview of Pre-clinical research
Drug development plays a vital role in recent days. Owing to the endeavors and efforts of the pharmaceutical industry, a variety of medications that cater to different diseases for various health issues have been developed.
The complete withstanding of the business in the pharmaceutical industry is entirely relies on innovation and outstanding results. The success of the company relies on the paved way of a streamline and the development of the drug process.
In the drug development process, preclinical research is of utmost importance to increase the chance of completing the clinical trial to the approval of a new drug. The FDA provides a detailed guideline to the drug development company for their complete involvement in the drug development process.
The doctors and researchers must find out whether the drug causes any potential harm to the people and it causes any major side effects on them. To test this drug, there are two types of preclinical research are undertaken: In Vitro and In Vivo
Types of Pre-clinical drug testing
Vivo Preclinical Drug Testing:
In the drug testing process, the preclinical research of Vivo and Vitro studies play an appropriate role in different situations. In vivo testing, before the launch of testing to the human body, the clinical study involves the form of testing subject to regulation and compliance standards.
In vivo testing, the testing is initially performed to the live animals and murine models in the laboratory. This testing is a generally expensive and time-intensive process than Vitro testing.
Vitro Preclinical Drug Testing:
In vitro testing, the testing process is done with an artificially controlled environment. In vitro process, the drug bypasses safety in favor of assessing drug efficacy. It is specifically used for cancer drug testing.
In vivo testing, clinical trials are not necessarily important. But in the case of Vitro setting, it is essentially important, as the test doesn’t give the complete picture of the human reaction to the drug.
Adapt the best testing for preclinical research
Vivo is more specific and reliable and it is a time taking process that needs the length of time to complete the tasks. It is a smart way to handle this testing if the budget and time are available on the research side.
But the Vitro testing process is done with a superfast process and the cost for this testing is comparatively less than Vivo setting. It also helps bring the new drug to the clinical trial faster than Vivo.
In an ideal scenario, both the pre-clinical research testing provides its best result. Researches launch a project under Vitro clinical review. At the same time, they do test in vivo strategy for drug safety and drug efficacy.