Failed IVF

Failed IVF

In-vitro fertilization is a complex medical procedure that requires a high degree of professionalism and in-depth knowledge on the part of doctors. In some cases, even IVF performed more than once does not bring the expected result. For many patients will be relevant information – why this method can become unsuccessful, and what should be done in such a case?

Unsuccessful IVF protocol is most often associated with the following reasons:

  • Poor quality of embryos;
  • Endometrial abnormalities;
  • fallopian tube diseases;
  • Endocrine system disorders.

Embryos with at least 6 cells and high fission rates are optimal for IVF. Their poor quality may be due to poor oocytes or sperm not having all the necessary indicators.

Successful embryo implantation and subsequent pregnancy largely depend on the condition of the endometrium. A favorable IVF outcome is possible only when the size of the endometrium is 7-14 mm. Various diseases – chronic endometritis, adenomyosis, polyposis, inflammatory processes in the cervical canal area – should also be excluded.

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Diseases of the fallopian tubes, provoking failure during IVF, occur in a variety of forms. Cervical factor infertility, untreated obstruction, hydrosalpinx lead to the absence of conception. The latter pathology provokes the accumulation of fluid inside the tubes, against which the embryo is deprived of the opportunity to develop normally.

Ovulation stimulation, which is one of the main stages of IVF, can cause a worsening of pre-existing endocrinological disorders. This is why patients wishing to undergo in vitro fertilization procedure, shows a consultation with an endocrinologist. It is especially important to get the advice of this doctor if in the past a woman had diseases such as diabetes, hypo-hyperthyroidism, hypo-hyperandrogenism.

If there have been failed IVF attempts, the reasons may lie in the presence of immune disorders, polycystic ovarian syndrome, adhesions in the pelvis, and chronic infections in the body. Lack of conception may be due to negative heredity or habitual failure to conceive.


Failed IVF attempts can be provoked by non-medical factors. Reasons for the absence of conception and pregnancy also include:

  • The age of the patient is less than 22 or more than 40 years old;
  • Excessive weight or obesity in a woman;
  • Bad habits of one or both partners (smoking, alcoholism, drug addiction).

The reasons why the embryo did not take root after IVF may be an emotional and psychological factor. The most important thing is a positive psychological mood of the woman before the upcoming procedure. If a patient is under stress or experiences increased emotional stress, the chances of pregnancy decrease significantly.

Specialists who perform IVF sometimes have to deal with a trivial failure.  This wording is used in the absence of any pronounced signs that could become an obstacle to a successful outcome.